Predictive value of procalcitonin in respiratory adenovirus infections in children with elevated C-reactive protein levels

Abstract: Adenoviruses (ADV) often cause respiratory infections. They have, in contrast to other respiratory viruses via a potential acute phase parameter (C-reactive protein, leukocytes and interleukin 6) to trigger. ADV infections are associated with increased secretion of IL-6 and TNF-?lpha, which activates the synthesis of acute phase proteins. The exact pathogenic mechanism is still unclear. Adenoviruses (ADV) often cause respiratory infections. They have, in contrast to other respiratory viruses via a potential acute phase parameter (C-reactive protein, leukocytes and interleukin 6) to trigger. ADV infections are associated with increased secretion of IL-6 and TNF-?lpha, which activates the synthesis of acute phase proteins. The exact pathogenic mechanism is still unclear. Procalcitonin (PCT) offers the possibility, particularly at elevated CRP levels between ADP and bacterial infections to distinguish and thus avoid antibiotic prescriptions.